kaurenoic acid
- Product Name
- kaurenoic acid
- CAS No.
- 6730-83-2
- Chemical Name
- kaurenoic acid
- Synonyms
- NSC 339145;kaurenoate;Cunabic acid;kaurenoic acid;Kauren-19-oic acid;ent-kaur-16-en-19-oicaci;Kaurane-16-ene-18-oic acid;(-)-Kaur-16-en-18-oic acid;ent-Kaur-16-en-19-oic acid;Kaur-16-en-18-oic acid,(4a)-
- CBNumber
- CB91316121
- Molecular Formula
- C20H30O2
- Formula Weight
- 302.45
- MOL File
- 6730-83-2.mol
kaurenoic acid Property
- Melting point:
- 171-172 °C
- Boiling point:
- 426.6±34.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 10 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 10 mg/ml
- form
- A solid
- pka
- 4.70±0.40(Predicted)
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SMB00177
- Product name
- Kaurenoic acid
- Purity
- ≥95% (LC/MS-ELSD)
- Packaging
- 1mg
- Price
- $489
- Updated
- 2024/03/01
- Product number
- PHL84229
- Product name
- Kaurenoic acid
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $574
- Updated
- 2024/03/01
- Product number
- 28957
- Product name
- Kaurenoic Acid
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 28957
- Product name
- Kaurenoic Acid
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 28957
- Product name
- Kaurenoic Acid
- Packaging
- 10mg
- Price
- $142
- Updated
- 2024/03/01
kaurenoic acid Chemical Properties,Usage,Production
Description
Kaurenoic acid is a diterpene that has been found in C. langsdorffii and has diverse biological activities, including anticancer, antibacterial, antioxidant, and anti-inflammatory properties. It is cytotoxic to 22Rv1 and LNCaP prostate, HT-29, HCT116, SW480, and SW620 colon, and MCF-7 breast cancer cells with IC50 values ranging from 15.03 to 48.87 μg/ml. Kaurenoic acid is active against S. epidermidis, S. capitis, E. faecalis, and S. haemolyticus in vitro (MICs = 6.25-12.5 μg/ml). Kaurenoic acid (50 and 100 mg/kg) reduces colonic myeloperoxidase (MPO) activity and malondialdehyde (MDA) levels in a rat model of acetic acid-induced colitis, as well as colonic tissue damage, leukocytic infiltration, and submucosal edema when administered at a dose of 100 mg/kg.
Uses
ent-Kaurenoic Acid can be used in biological study. Kinetic profile of guaco syrup metabolites like coumarin, 7-hydroxycoumarin, o-coumaric acid, kaurenoic acid can be performed for identification of alternative route of coumarin metabolism in human plasma.
Definition
ChEBI: An ent-kaurane diterpenoid that is ent-kauran-19-oic acid in which a double bond is present at position 16(17); exhibits anticancer and anti-HIV 1 activity.
kaurenoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
kaurenoic acid Suppliers
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View Lastest Price from kaurenoic acid manufacturers
- Product
- kaurenoic acid 6730-83-2
- Price
- US $8.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-23
- Product
- Kaurenoic acid 6730-83-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-25
- Product
- kaurenoic acid 6730-83-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%HPLC
- Supply Ability
- 10 tons
- Release date
- 2020-01-09